TECHNOLOGY
PLATFORM
Origenis’ patented technology platform MOREsystem® is unique,
fast, and highly integrated. An interdisciplinary team of
scientists has developed it over several years. The technology
platform has been validated in several collaborations with big
pharma and biotech companies in the past and is now applied for
origenis’ partners.
Origenis offers tangible advantages to its customers.
1. exploitation of
new chemical dimensions
MOREsystem® allows the direct exploitation of huge chemical spaces
(more than 1.000.000.000.000 distinct compounds) not accessible by
any other method. Origenis can synthesize every selected compound
of these immense chemical spaces in a straightforward synthetic
route resulting in more patentable drug candidates in less
time.
2. benefits from
system integration
MOREsystem® is a fully integrated system. Molecular design,
chemistry, biology, data-handling and logistics are interlinked
with creative algorithms resulting in a fast process that can
follow multiple hypotheses while reducing human error.
3. faster
optimization through multiparametric
approach
MOREsystem® produces better leads by tailoring compound properties
towards their desired therapeutic use right from the project start.
Origenis’ customizable multi-parametric optimization ensures
that most pre-clinical requirements are met resulting in a
reduction of expensive and time-consuming MedChem
modifications.
4. reduction of
attrition rate in drug discovery
MOREsystem® produces optimized lead compound series in a direct
approach. This shortcut results in a lower attrition rate compared
to the common multi-stage drug discovery with hit finding, hit
validation, hit-to-lead, and lead optimization. As a result time
and costs of your research are reduced.
